CMS challenge model
We have been working for a long time to develop a challenge model for cardiomyopathy syndrome (CMS). We have finally succeeded, and are able to offer challenge with PMCV (piscine myocarditis virus). Nine weeks after challenge by i.p. or i.m. injection we found histopathological changes consistent with CMS in the heart. The findings correlated well with the viral load detected by qPCR.