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Challenge models

Challenge models

VESO is dedicated to providing valid and relevant pre-clinical and clinical trial data through in vivo fish trials with focus on vaccines and pharmaceuticals, health feeds, and genetic resistance profiles. We also offer long-term studies to evaluate the duration of protection (DOP) after vaccination. Duration trials can be run in parallel with field trials. Data from such studies are important to demonstrate to which extent the fish are protected throughout the production cycle. A selection of our well-established challenge models is listed below. Please contact Marie Løvoll or Valentina Tapia for further information.

Species Pathogen Disease Facility
Atlantic salmon Lepeophtheirus salmonis Sea lice Norway
Atlantic salmon/ coho salmon/ rainbow trout Caligus rogercresseyi Sea lice/ caligus Chile
Atlantic salmon Paramoeba perurans Amoebic gill disease (AGD) Norway
Atlantic salmon Piscine orthoreovirus (PRV) Heart and skeletal muscle inflammation (HSMI) Norway
Atlantic salmon Piscine myocarditis virus (PMCV) Cardiomyopathy syndrome (CMS) Norway
Atlantic salmon Salmon pancreatic disease virus (SPDV - SAV2/3) Pancreas disease (PD) Norway
Atlantic salmon Infectious salmon anemia virus (ISAV) Infectious salmon anemia (ISA) Norway
Atlantic salmon/ rainbow trout Infectious pancreatic necrosis virus (IPNV) Infectious pancreatic necrosis (IPN) Norway
Atlantic salmon/ coho salmon/ rainbow trout Piscirickettsia salmonis Salmon rickettsial syndrome (SRS) Chile/ Norway
Atlantic salmon Yersinia ruckeri Yersiniosis/ Enteric redmouth disease (ERM) Norway
Atlantic salmon Moritella viscosa Winter ulcers Norway
Atlantic salmon Vibrio ordalii Vibriosis Norway
Atlantic salmon/ rainbow trout Vibrio anguillarum O1 Vibriosis Norway
Atlantic salmon/ rainbow trout Vibrio anguillarum O2a Vibriosis Norway
Atlantic salmon Vibrio salmonicida Cold water vibriosis (Hitra disease) Norway
Atlantic salmon/ rainbow trout Aeromonas salmonicida Furunculosis Norway
Seabass Photobacterium damselae Pasteurellosis Norway
Seabass Vibrio anguillarum Vibriosis Norway
Lumpfish Vibrio anguillarum Vibriosis Norway
Lumpfish Atypical Aeromonas salmonicida Atypical furunculosis Norway
Lumpfish Pasteurella sp Pasteurellosis Norway
Atlantic cod Vibrio anguillarum O1 Vibriosis Norway
Atlantic cod Vibrio anguillarum O2a Vibriosis Norway
Atlantic cod Vibrio anguillarum O2b Vibriosis Norway
Atlantic cod Francisella Francisellosis Norway